Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456837 | 0.80 | L3MBTL1 (0.50) | L3MBTL1LMNAABCB1TUBB3GAA | |
| SCHEMBL30118652 | 0.80 | GAA (0.36) | L3MBTL1LMNAABCB1TUBB3GAA | |
| SCHEMBL23975966 | 0.80 | GAA (0.36) | L3MBTL1LMNAABCB1TUBB3GAA | |
| SCHEMBL30225145 | 0.78 | ACHE (0.38) | LMNAABCB1TUBB3GAACYP1A2 | |
| SCHEMBL23976664 | 0.78 | ABCB1 (0.33) | L3MBTL1LMNAABCB1TUBB3GAA | |
| SCHEMBL23975725 | 0.78 | ACHE (0.38) | LMNAABCB1TUBB3GAACYP1A2 | |
| SCHEMBL23975849 | 0.77 | USP2 (0.32) | L3MBTL1LMNAABCB1TUBB3GAA | |
| SCHEMBL30225350 | 0.74 | GAA (0.38) | L3MBTL1LMNAGAACYP1A2TSHR | |
| SCHEMBL23975730 | 0.74 | POLB (0.40) | L3MBTL1LMNAGAACYP1A2ALDH1A1 | |
| SCHEMBL23975870 | 0.74 | USP2 (0.35) | L3MBTL1LMNAABCB1TUBB3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222483-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |