Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083210 | 0.76 | KDM4E (0.41) | MAPTKDM4ECCNA2CDK2KMT2A | |
| SCHEMBL14239714 | 0.75 | LMNA (0.50) | MAPTKMT2ACYP2C19CYP2C9CYP1A2 | |
| SCHEMBL30421055 | 0.71 | NPSR1 (0.55) | MAPTKDM4EKMT2ACYP2C19CYP3A4 | |
| SCHEMBL1430701 | 0.71 | NPSR1 (0.55) | MAPTKDM4EKMT2ACYP2C19CYP3A4 | |
| SCHEMBL24645772 | 0.71 | MAPT (0.67) | MAPTKDM4EKMT2ACYP2C19CYP3A4 | |
| SCHEMBL15061717 | 0.70 | KMT2A (0.50) | MAPTKDM4EKMT2ACYP2C19CYP3A4 | |
| SCHEMBL7964257 | 0.69 | SMN1; SMN2 (0.54) | MAPTKDM4EKMT2ACYP2C19CYP3A4 | |
| SCHEMBL1164174 | 0.69 | LMNA (0.43) | MAPTKDM4ECCNA2CDK2CYP2C19 | |
| SCHEMBL50482 | 0.69 | MAPT (0.69) | MAPTKDM4EKMT2ACYP2C19CYP1A2 | |
| SCHEMBL23976747 | 0.68 | KDM4E (0.58) | KDM4EL3MBTL1ALDH1A1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904349-A2 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}HETEROCYCLYL AMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |