Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.67 |
| ▸ | SCN2A | Q99250 | 6/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 3/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17810015 | 0.86 | HDAC1 (0.59) | SCN10ASCN2AXDHMKNK1MKNK2 | |
| SCHEMBL25003830 | 0.84 | SCN10A (0.65) | SCN10ASCN2AMAP4K4XDHMKNK1 | |
| SCHEMBL17806746 | 0.82 | MKNK1 (0.52) | SCN10AXDHMKNK1MKNK2PIK3CD | |
| SCHEMBL4592444 | 0.81 | CYP11B1 (0.62) | SCN10ASCN2AMAP4K4XDHMKNK1 | |
| SCHEMBL1840398 | 0.80 | MKNK1 (0.68) | SCN10ASCN2AMAP4K4XDHMKNK1 | |
| SCHEMBL17045484 | 0.80 | HCAR2 (0.60) | SCN10ASCN2AMKNK1MKNK2PIK3CD | |
| SCHEMBL1132053 | 0.79 | HDAC2 (0.57) | MKNK1MKNK2 | |
| SCHEMBL13876392 | 0.78 | SCN10A (0.61) | SCN10ASCN2AMAP4K4XDH | |
| SCHEMBL5909485 | 0.77 | RAF1 (0.53) | MKNK1MKNK2RAF1 | |
| SCHEMBL28800805 | 0.77 | PIK3CD (0.57) | SCN10ASCN2AXDHMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904349-A2 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}HETEROCYCLYL AMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |