⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23977202 | 0.85 | — | — | |
| SCHEMBL30060673 | 0.85 | — | — | |
| SCHEMBL23987331 | 0.79 | — | — | |
| SCHEMBL25739527 | 0.74 | CYP1A2 (0.38) | — | |
| SCHEMBL23976794 | 0.71 | LMNA (0.34) | — | |
| SCHEMBL14558302 | 0.68 | CCR1 (0.37) | — | |
| SCHEMBL2113347 | 0.67 | — | — | |
| SCHEMBL2909172 | 0.67 | CCR1 (0.35) | — | |
| SCHEMBL20865971 | 0.66 | NOS2 (0.35) | — | |
| SCHEMBL27284643 | 0.66 | NOS2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217508-A1 | COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF HIF2α AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-11-04 | — | — | WO | disclosed |