SCHEMBL2397727

SCHEMBL2397727

CCCNC(=O)OCc1c2ccccc2cc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.55
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
NCEH1 Q6PIU2 1/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TACR1 P25103 1/20 0.41
HTT P42858 1/20 0.40
HPGD P15428 1/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23228332 0.92 EPHX1 (0.53) EPHX1NCEH1HTT
SCHEMBL25763415 0.89 EPHX1 (0.51) EPHX1NCEH1
SCHEMBL23527762 0.88 EPHX1 (0.58) EPHX1KDM4EALDH1A1NCEH1LMNA
SCHEMBL12123498 0.88 SMN1; SMN2 (0.53) EPHX1KDM4EALDH1A1NCEH1LMNA
SCHEMBL30821051 0.87 EPHX1 (0.56) EPHX1NCEH1LMNASMN1; SMN2KMT2A
SCHEMBL18412607 0.87 EPHX1 (0.56) EPHX1NCEH1LMNASMN1; SMN2KMT2A
SCHEMBL13399559 0.84 EPHX1 (0.49) EPHX1NCEH1MEN1KMT2AHTT
SCHEMBL18829022 0.84 EPHX1 (0.49) EPHX1NCEH1LMNASMN1; SMN2MAPT
SCHEMBL16317577 0.84 EPHX1 (0.51) EPHX1KDM4EALDH1A1HTTHPGD
SCHEMBL13399659 0.83 EPHX1 (0.53) EPHX1KDM4EALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616337-A Film forming material for semiconductor, member forming material for semiconductor, process member forming material for semiconductor, underlayer film forming material, underlayer film, and semiconductor device 株式会社艾迪科 2024-02-27 CN disclosed
CN-114502680-B Adhesive composition 住友化学株式会社 2023-12-01 CN disclosed
US-8957212-B2 Photobase generator WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-02-17 US disclosed
CN-104285168-A Polarizing plate SUMITOMO CHEMICAL CO 2015-01-14 CN disclosed
EP-2368875-B1 PHOTOBASE GENERATOR WAKO PURE CHEM IND LTD (JP) 2014-09-03 EP disclosed
US-8323745-B2 Application liquid and method for formation of a silica-based coating film using the application liquid TOKYO OHKA KOGYO CO., LTD. (JP) 2012-12-04 US disclosed
US-8323745-B2 Application liquid and method for formation of a silica-based coating film using the application liquid TOKYO OHKA KOGYO CO., LTD. (JP) 2012-12-04 US disclosed
US-20110233048-A1 PHOTOBASE GENERATOR WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-29 US disclosed
US-20110233048-A1 PHOTOBASE GENERATOR WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-29 US disclosed
EP-2368875-A1 PHOTOBASE GENERATOR Wako Pure Chemical Industries, Ltd. (JP) 2011-09-28 EP disclosed
EP-2368875-A1 PHOTOBASE GENERATOR Wako Pure Chemical Industries, Ltd. (JP) 2011-09-28 EP disclosed
US-20100247799-A1 APPLICATION LIQUID AND METHOD FOR FORMATION OF A SILICA-BASED COATING FILM USING THE APPLICATION LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2010-09-30 US disclosed
US-20100247799-A1 APPLICATION LIQUID AND METHOD FOR FORMATION OF A SILICA-BASED COATING FILM USING THE APPLICATION LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110233048-A1 PHOTOBASE GENERATOR CYBA, CRY1, GNB1 EPHX1 2562/4885KDM4E 3712/4885ALDH1A1 503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.