SCHEMBL23977388

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25909525	0.88	STAT3 (0.39)	ALDH1A1KDM4EKMT2ASTAT3CA1
	SCHEMBL31723841	0.83	SMN1; SMN2 (0.45)	ALDH1A1MAPTSMN1; SMN2HTTKMT2A
	SCHEMBL25909219	0.82	HRH3 (0.40)	ALDH1A1MAPTKDM4ESTAT3CA1
	SCHEMBL25972575	0.81	STAT3 (0.38)	ALDH1A1KMT2ASTAT3CA1CA9
	SCHEMBL31723903	0.81	MBOAT4 (0.37)	ALDH1A1MAPTSMN1; SMN2HTTKDM4E
	SCHEMBL23977288	0.80	CA1 (0.35)	ALDH1A1STAT3CA1CA9CA12
	SCHEMBL2130361	0.79	CA12 (0.37)	ALDH1A1SMN1; SMN2KMT2ASTAT3EGFR
	SCHEMBL30047078	0.79	GBA1 (0.40)	ALDH1A1KDM4E
	SCHEMBL1126532	0.79	GBA1 (0.40)	ALDH1A1KDM4E
	SCHEMBL7909564	0.77	CA2 (0.54)	ALDH1A1MAPTKDM4EKMT2ASTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.