SCHEMBL2397764

SCHEMBL2397764

O=C(Nc1cccc(NC(=O)c2ccc(F)cc2)n1)c1ccc(F)cc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.71
MEN1 O00255 6/20 0.70
KMT2A Q03164 6/20 0.70
GRM5 P41594 2/20 0.58
HTR1F P30939 2/20 0.58
LMNA P02545 1/20 0.56
KCNK3 O14649 1/20 0.56
KCNK9 Q9NPC2 1/20 0.56
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.54
PTPN1 P18031 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28808130 0.89 CHRNB2 (0.60) RXFP1MEN1KMT2AGRM5HTR1F
SCHEMBL28326270 0.89 GRM5 (0.76) KMT2AGRM5LMNANPC1RAB9A
SCHEMBL1196671 0.89 RXFP1 (0.57) RXFP1MEN1KMT2AGRM5HTR1F
SCHEMBL28937159 0.89 MEN1 (0.60) RXFP1MEN1KMT2AGRM5HTR1F
SCHEMBL16899211 0.88 NPC1 (0.64) RXFP1MEN1KMT2AGRM5HTR1F
SCHEMBL28937134 0.85 MAPT (0.64) RXFP1MEN1KMT2AGRM5HTR1F
SCHEMBL25383671 0.83 KMT2A (0.53) RXFP1MEN1KMT2AGRM5HTR1F
SCHEMBL821839 0.82 KMT2A (1.00) RXFP1MEN1KMT2AGRM5NPC1
SCHEMBL12250622 0.81 RXFP1 (0.71) RXFP1MEN1KMT2AGRM5LMNA
SCHEMBL4582098 0.81 RAB9A (0.83) MEN1KMT2ALMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8604135-B2 Thermally reversible cross-linked poly(aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-12-10 US disclosed
US-8337954-B2 Thermally reversible cross-linked poly (aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-12-25 US disclosed
US-8337954-B2 Thermally reversible cross-linked poly (aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-12-25 US disclosed
US-8337954-B2 Thermally reversible cross-linked poly (aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-12-25 US disclosed
US-20110257344-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY(ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-10-20 US disclosed
US-20110257344-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY(ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-10-20 US disclosed
US-8012541-B2 Thermally reversible cross-linked poly (aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-09-06 US disclosed
US-8012541-B2 Thermally reversible cross-linked poly (aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-09-06 US disclosed
US-8012541-B2 Thermally reversible cross-linked poly (aryl ether ketone) media and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-09-06 US disclosed
US-7854878-B2 surfaces of the Au doped cobalt nanoparticles are functionalized with 7-(5-uracil-ylcarbamoyl)heptanoic acid, enhancing ferromagnetism, providing a polyether having a functional group e.g. guanidinium, uracilyl, urea, imine, amide, or amine groups, functionalized nanoparticle form H2 bond with polymer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-21 US disclosed
US-7854878-B2 surfaces of the Au doped cobalt nanoparticles are functionalized with 7-(5-uracil-ylcarbamoyl)heptanoic acid, enhancing ferromagnetism, providing a polyether having a functional group e.g. guanidinium, uracilyl, urea, imine, amide, or amine groups, functionalized nanoparticle form H2 bond with polymer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-21 US disclosed
US-20090184445-A1 surfaces of the Au doped cobalt nanoparticles are functionalized with 7-(5-uracil-ylcarbamoyl)heptanoic acid, enhancing ferromagnetism, providing a polyether having a functional group e.g. guanidinium, uracilyl, urea, imine, amide, or amine groups, functionalized nanoparticle form H2 bond with polymer GLOBALFOUNDRIES U.S. INC. 2009-07-23 US disclosed
US-20090184445-A1 surfaces of the Au doped cobalt nanoparticles are functionalized with 7-(5-uracil-ylcarbamoyl)heptanoic acid, enhancing ferromagnetism, providing a polyether having a functional group e.g. guanidinium, uracilyl, urea, imine, amide, or amine groups, functionalized nanoparticle form H2 bond with polymer GLOBALFOUNDRIES U.S. INC. 2009-07-23 US disclosed
US-20080186612-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE DIPIETRO RICHARD ANTHONY 2008-08-07 US disclosed
US-20080186612-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE DIPIETRO RICHARD ANTHONY 2008-08-07 US disclosed
US-20080186612-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE DIPIETRO RICHARD ANTHONY 2008-08-07 US disclosed
US-20080175139-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE INTERNATIONAL BUSINESS MACHINES CORPORATION 2008-07-24 US disclosed
US-20080175139-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE INTERNATIONAL BUSINESS MACHINES CORPORATION 2008-07-24 US disclosed
US-20080175139-A1 THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE INTERNATIONAL BUSINESS MACHINES CORPORATION 2008-07-24 US disclosed