Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15009200 | 0.84 | MEN1 (0.49) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL15029047 | 0.84 | HDAC6 (0.48) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL3360337 | 0.81 | CNR2 (0.46) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL25775845 | 0.74 | CNR2 (0.43) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL1072145 | 0.72 | POLB (0.60) | CNR2KDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL2408019 | 0.72 | KDM4E (0.44) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL2408017 | 0.72 | KDM4E (0.44) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL16884342 | 0.72 | CNR2 (0.39) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL15009152 | 0.72 | ALDH1A1 (0.44) | CNR2HDAC6KDM4EALDH1A1TRPV6 | |
| SCHEMBL16884266 | 0.71 | KDM4E (0.36) | CNR2HDAC6KDM4EALDH1A1TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203022-A1 | HETEROCYCLE AND GLUTARIMIDE SKELETON-BASED COMPOUND AND APPLICATIONS THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2023-06-29 | — | — | US | disclosed |
| WO-2021219078-A1 | HETEROCYCLE AND GLUTARIMIDE SKELETON-BASED COMPOUND AND APPLICATIONS THEREOF | 上海科技大学 (CN) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203022-A1 | HETEROCYCLE AND GLUTARIMIDE SKELETON-BASED COMPOUND AND APPLICATIONS THEREOF | TNF, GCDH, LITAF | CNR2 2547/4885HDAC6 452/4885KDM4E 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.