SCHEMBL239781

SCHEMBL239781

C=CCc1cc(Cc2ccc(OC)c(CC=C)c2)ccc1OC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 8/20 0.63
GABRB2 P47870 8/20 0.63
ALOX5 P09917 4/20 0.63
CNR2 P34972 2/20 0.63
ALDH1A1 P00352 4/20 0.61
PPARG P37231 1/20 0.61
PPARD Q03181 1/20 0.61
PPARA Q07869 1/20 0.61
CA2 P00918 1/20 0.55
PTGS1 P23219 2/20 0.51
CYP3A4 P08684 2/20 0.51
AR P10275 1/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
GAA P10253 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4983937 0.86 GABRA1 (0.60) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL4877248 0.86 GABRA1 (0.60) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL4877224 0.86 GABRA1 (0.60) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL251558 0.81 GABRA1 (0.71) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL12907781 0.81 CNR2 (0.45) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL2848289 0.80 ALOX5 (0.56) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL21358033 0.80 GABRA1 (0.56) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL3951418 0.80 GABRA1 (0.56) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL10328509 0.80 GABRA1 (0.56) GABRA1GABRB2ALOX5CNR2ALDH1A1
SCHEMBL21359988 0.80 CNR2 (0.53) GABRA1GABRB2ALOX5CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
EP-2417168-A1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS Huntsman Advanced Materials Americas LLC (US) 2012-02-15 EP disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 US disclosed
US-5138000-A High strength molding material CIBA-GEIGY CORPORATION (US) 1992-08-11 US disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0385937-A1 Curable blends based on aromatic bismaleinimides CIBA-GEIGY AG (CH) 1990-09-05 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 EP disclosed
US-4689378-A Stable imide-containing composition from diamino phenyl indane-bis-maleimide and alkenyl phenol CIBA-GEIGY CORPORATION (US) 1987-08-25 US disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP disclosed