Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978366 | 0.76 | — | — | |
| SCHEMBL30309599 | 0.71 | LCK (0.41) | CCND3CDK6 | |
| SCHEMBL23978358 | 0.71 | LCK (0.41) | CCND3CDK6 | |
| SCHEMBL30309493 | 0.71 | CYP1A2 (0.39) | CCND3CDK6TRPV4 | |
| SCHEMBL30309501 | 0.71 | CCND3 (0.36) | CCND3CDK6TRPV4 | |
| SCHEMBL30309547 | 0.71 | TRPV4 (0.38) | CCND3CDK6TRPV4 | |
| SCHEMBL23978116 | 0.71 | TRPV4 (0.38) | CCND3CDK6TRPV4 | |
| SCHEMBL23978179 | 0.71 | CCND3 (0.36) | CCND3CDK6TRPV4 | |
| SCHEMBL23978363 | 0.71 | CYP1A2 (0.39) | CCND3CDK6TRPV4 | |
| SCHEMBL25886882 | 0.71 | CCND3 (0.33) | CCND3CDK6TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219731-A2 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2021-11-04 | — | — | WO | disclosed |