Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 3/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NMT1 | P30419 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978179 | 1.00 | CCND3 (0.36) | CCND3CDK6KDM4ENMT1CDK2 | |
| SCHEMBL23978363 | 0.82 | CYP1A2 (0.39) | CCND3CDK6TRPV4LMNAPDE10A | |
| SCHEMBL30309493 | 0.82 | CYP1A2 (0.39) | CCND3CDK6TRPV4LMNAPDE10A | |
| SCHEMBL30309599 | 0.81 | LCK (0.41) | CCND3CDK6LMNACCNKCDK9 | |
| SCHEMBL23978358 | 0.81 | LCK (0.41) | CCND3CDK6LMNACCNKCDK9 | |
| SCHEMBL23978116 | 0.80 | TRPV4 (0.38) | CCND3CDK6CDK2CCNE2CCNE1 | |
| SCHEMBL30309547 | 0.80 | TRPV4 (0.38) | CCND3CDK6CDK2CCNE2CCNE1 | |
| SCHEMBL23978127 | 0.77 | TRPV4 (0.35) | CCND3CDK6CDK2CCNE2CCNE1 | |
| SCHEMBL30309532 | 0.77 | TRPV4 (0.35) | CCND3CDK6CDK2CCNE2CCNE1 | |
| SCHEMBL23978385 | 0.76 | TRPV4 (0.34) | CCND3CDK6TRPV4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143191-A2 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | iOmx Therapeutics AG (DE) | 2023-03-08 | — | — | EP | disclosed |