Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398484 | 0.88 | SLC1A3 (0.58) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| SCHEMBL5555264 | 0.85 | KMT2A (0.53) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| SCHEMBL12757430 | 0.84 | MAPT (0.49) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| SCHEMBL23978690 | 0.83 | ALDH1A1 (0.49) | BCAT2SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL8695483 | 0.83 | ALDH1A1 (0.51) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| SCHEMBL598314 | 0.82 | DPP8 (0.52) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| SCHEMBL598313 | 0.82 | DPP8 (0.52) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| SCHEMBL23489415 | 0.81 | ALDH1A1 (0.44) | SLC6A2SLC6A3KMT2ATDP1SLC1A3 | |
| Trifluoroacetic Acid SCHEMBL20263694 | 0.80 | SLC1A3 (0.51) | KMT2ASLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL17878732 | 0.80 | SYK (0.65) | KMT2ASLC1A3SLC1A1IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |