SCHEMBL5555264

SCHEMBL5555264

NC(CNCC(N)C(=O)OCc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
SLC1A1 P43005 4/20 0.50
ALDH1A1 P00352 3/20 0.50
SLC1A3 P43003 3/20 0.50
SLC1A2 P43004 2/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
IDO1 P14902 1/20 0.49
LMNA P02545 1/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046848 0.89 KMT2A (0.46) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL8256163 0.89 KMT2A (0.46) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL8695483 0.87 ALDH1A1 (0.51) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL23978728 0.85 BCAT2 (0.49) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL29398484 0.85 SLC1A3 (0.58) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL218262 0.82 ALDH1A1 (0.53) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL22535897 0.82 ALDH1A1 (0.53) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL22535886 0.82 ALDH1A1 (0.53) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL218263 0.82 ALDH1A1 (0.53) KMT2ASLC6A2SLC6A3TDP1SLC1A1
SCHEMBL73708 0.82 SLC7A5 (0.63) KMT2ASLC6A2SLC6A3TDP1SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211241-B2 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes SCHERING AKTIENGESELLSCHAFT (DE) 2007-05-01 US disclosed
US-6861043-B2 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes SCHERING AG (DE) 2005-03-01 US disclosed
US-20040091426-A1 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-05-13 US disclosed
EP-0768898-B1 CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME SCHERING AG (DE) 2003-04-09 EP disclosed
US-20020187101-A1 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes SCHERING AG (DE) 2002-12-12 US disclosed
US-6426059-B1 NUCLEAR MAGNETIC RESONANCE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2002-07-30 US disclosed
US-6248306-B1 MEDICAL DIAGNOSIS SCHERING AKTIENGESELLSCHAFT (DE) 2001-06-19 US disclosed
US-6177060-B1 NMR OR X-RAY LYMPHOGRAPHY IMAGES SCHERING AKTIENGESEUSCHAFT (DE) 2001-01-23 US disclosed
US-6166200-A Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes SCHERING AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
US-6063361-A ADMINISTERING TO A PATIENT AT LEAST ONE CASCADE POLYMER COMPLEX AND SUBJECTING THE PATIENT TO A RADIOLOGY DIAGNOSIS SCHERING AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
US-5919433-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-06 US disclosed
US-5820849-A DIAGNOSIS WITH NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1998-10-13 US disclosed
EP-0832150-A1 CASCADE POLYMERS WITH IODINE-CONTAINING AROMATIC COMPOUNDS SCHERING AKTIENGESELLSCHAFT (DE) 1998-04-01 EP disclosed
EP-0768898-A1 CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-23 EP disclosed
WO-1996041830-A1 CASCADE POLYMERS WITH IODINE-CONTAINING AROMATIC COMPOUNDS SCHERING AKTIENGESELLSCHAFT (DE) 1996-12-27 WO disclosed
WO-1996001655-A1 CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME SCHERING AKTIENGESELLSCHAFT (DE) 1996-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040091426-A1 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes ZYX, CCNY, MOK KMT2A 1168/4885SLC6A2 4480/4885SLC6A3 4599/4885
US-20020187101-A1 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes TFPI, LYN, SYK KMT2A 4826/4885SLC6A2 4817/4885SLC6A3 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.