Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978779 | 0.88 | EPHX2 (0.54) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL23978767 | 0.87 | EPHX2 (0.58) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL30083831 | 0.87 | EPHX2 (0.58) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL24803485 | 0.87 | EPHX2 (0.58) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL23978772 | 0.87 | EPHX2 (0.58) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL30083826 | 0.87 | EPHX2 (0.58) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL30279387 | 0.83 | EPHX2 (0.53) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL29019148 | 0.82 | EPHX2 (0.55) | EPHX2HTTUSP2ALDH1A1 | |
| SCHEMBL24805452 | 0.82 | EPHX2 (0.55) | EPHX2HTTUSP2TSHRALDH1A1 | |
| SCHEMBL23978680 | 0.82 | EPHX2 (0.39) | EPHX2HTTUSP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |