Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279387 | 0.92 | EPHX2 (0.53) | EPHX2HRH1CASP1ALDH1A1CTSK | |
| SCHEMBL29019175 | 0.85 | EPHX2 (0.48) | EPHX2ALDH1A1USP2HTT | |
| SCHEMBL24805458 | 0.85 | EPHX2 (0.50) | EPHX2CASP1ALDH1A1USP2HTT | |
| SCHEMBL30083843 | 0.85 | EPHX2 (0.50) | EPHX2CASP1ALDH1A1USP2HTT | |
| SCHEMBL24804772 | 0.85 | EPHX2 (0.50) | EPHX2CASP1ALDH1A1USP2HTT | |
| SCHEMBL23978768 | 0.84 | ALDH1A1 (0.52) | EPHX2ALDH1A1IDO1USP2HTT | |
| SCHEMBL24804266 | 0.84 | ALDH1A1 (0.52) | EPHX2ALDH1A1IDO1USP2HTT | |
| SCHEMBL24804267 | 0.84 | ALDH1A1 (0.52) | EPHX2ALDH1A1IDO1USP2HTT | |
| SCHEMBL30279443 | 0.84 | ALDH1A1 (0.52) | EPHX2ALDH1A1IDO1USP2HTT | |
| SCHEMBL23978779 | 0.83 | EPHX2 (0.54) | EPHX2ALDH1A1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |