Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019148 | 0.92 | EPHX2 (0.55) | EPHX2USP2CASP1HRH1CTSK | |
| SCHEMBL30083843 | 0.87 | EPHX2 (0.50) | EPHX2USP2CASP1ALDH1A1HTT | |
| SCHEMBL24804772 | 0.87 | EPHX2 (0.50) | EPHX2USP2CASP1ALDH1A1HTT | |
| SCHEMBL24805458 | 0.87 | EPHX2 (0.50) | EPHX2USP2CASP1ALDH1A1HTT | |
| SCHEMBL24106073 | 0.85 | USP2 (0.54) | EPHX2USP2TSHRALDH1A1HTT | |
| SCHEMBL23979138 | 0.84 | USP2 (0.58) | EPHX2USP2TSHRALDH1A1HTT | |
| SCHEMBL23978779 | 0.83 | EPHX2 (0.54) | EPHX2USP2TSHRALDH1A1HTT | |
| SCHEMBL23978737 | 0.83 | EPHX2 (0.58) | EPHX2USP2TSHRALDH1A1HTT | |
| SCHEMBL23978767 | 0.81 | EPHX2 (0.58) | EPHX2USP2TSHRALDH1A1HTT | |
| SCHEMBL23978772 | 0.81 | EPHX2 (0.58) | EPHX2USP2TSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |