Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231916 | 0.84 | HPGD (0.39) | TSHRHSP90AA1HSP90AB1 | |
| SCHEMBL23978848 | 0.78 | — | — | |
| SCHEMBL2016516 | 0.77 | TSHR (0.47) | TSHR | |
| SCHEMBL23978714 | 0.70 | CYP19A1 (0.35) | — | |
| SCHEMBL23978863 | 0.70 | NPC1 (0.41) | — | |
| SCHEMBL2015853 | 0.68 | MAOA (0.55) | TSHR | |
| SCHEMBL11698982 | 0.68 | CYP19A1 (0.34) | TSHR | |
| SCHEMBL24162342 | 0.68 | — | — | |
| SCHEMBL25914604 | 0.68 | RXRA (0.34) | TSHR | |
| SCHEMBL2263489 | 0.68 | NR1I2 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |