Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.49 |
| ▸ | CTSS | P25774 | 10/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29157629 | 1.00 | CTSK (0.49) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL1626495 | 0.88 | CTSS (0.54) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL3544394 | 0.88 | CTSS (0.54) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL5019146 | 0.88 | CTSS (0.54) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL15328418 | 0.88 | CTSS (0.47) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL15328420 | 0.88 | CTSS (0.47) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL25249372 | 0.88 | CTSS (0.47) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL4097845 | 0.88 | CTSS (0.47) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL29157630 | 0.87 | CTSK (0.46) | CTSKCTSSCTSLCTSB | |
| SCHEMBL29157633 | 0.87 | CTSK (0.46) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247339-B | Preparation method of alkylamine derivative | 潍坊富邦药业有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-117247339-A | Preparation method of alkylamine derivative | 潍坊富邦药业有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247339-B | Preparation method of alkylamine derivative | 潍坊富邦药业有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117247339-A | Preparation method of alkylamine derivative | 潍坊富邦药业有限公司 | 2023-12-19 | — | — | CN | disclosed |
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |