Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23979029 | 0.89 | TRPV1 (0.46) | EPHX2LIPGTRPV1CA1CA2 | |
| SCHEMBL23978895 | 0.89 | TRPV1 (0.46) | EPHX2LIPGTRPV1CA1CA2 | |
| SCHEMBL30083831 | 0.88 | EPHX2 (0.58) | EPHX2LIPGKMT2ATAOK1TAOK3 | |
| SCHEMBL30083826 | 0.88 | EPHX2 (0.58) | EPHX2LIPGKMT2ATAOK1TAOK3 | |
| SCHEMBL24803485 | 0.88 | EPHX2 (0.58) | EPHX2LIPGKMT2ATAOK1TAOK3 | |
| SCHEMBL23978767 | 0.88 | EPHX2 (0.58) | EPHX2LIPGKMT2ATAOK1TAOK3 | |
| SCHEMBL23978772 | 0.88 | EPHX2 (0.58) | EPHX2LIPGKMT2ATAOK1TAOK3 | |
| SCHEMBL23978826 | 0.80 | HTT (0.54) | EPHX2KMT2AHTTMEN1TSHR | |
| SCHEMBL30083834 | 0.80 | HTT (0.54) | EPHX2KMT2AHTTMEN1TSHR | |
| SCHEMBL24804276 | 0.80 | HTT (0.54) | EPHX2KMT2AHTTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643388-B2 | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643388-B2 | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | ITGB1, ITGB2, ITGA2 | EPHX2 1037/4885LIPG 2259/4885TRPV1 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.