Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26996981 | 0.85 | HDAC3 (0.38) | PRCPOPRM1KDM1ADRD2 | |
| SCHEMBL22808526 | 0.85 | HDAC3 (0.38) | PRCPOPRM1KDM1ADRD2 | |
| SCHEMBL26996830 | 0.85 | PRCP (0.36) | CRHR1PRCPOPRM1KDM1ADRD2 | |
| SCHEMBL23978833 | 0.83 | CRHR1 (0.43) | CRHR1KDM1AMAOBMAOA | |
| SCHEMBL13948436 | 0.81 | CRHR1 (0.40) | CRHR1PRCPOPRM1DRD2 | |
| SCHEMBL1911351 | 0.81 | CRHR1 (0.40) | CRHR1PRCPOPRM1DRD2 | |
| SCHEMBL1911359 | 0.81 | CRHR1 (0.40) | CRHR1PRCPOPRM1DRD2 | |
| SCHEMBL16388970 | 0.81 | CRHR1 (0.40) | CRHR1PRCPOPRM1DRD2 | |
| SCHEMBL22872971 | 0.81 | CHRNB2 (0.36) | PRCPOPRM1KDM1ADRD2 | |
| SCHEMBL25287428 | 0.81 | KDM1A (0.41) | CRHR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222614-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-11-04 | — | — | WO | disclosed |