SCHEMBL23979292

SCHEMBL23979292

Cc1n[nH]c(C)c1Cc1sc2c(c1C(=O)C1CC[C@@H](O)C1)c(=O)n(C)c(=O)n2CC(C)C

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC16A1 P53985 19/20 0.69
CYP2C9 P11712 15/20 0.69
CYP3A4 P08684 9/20 0.69
SLC16A3 O15427 1/20 0.69
SLC16A7 O60669 1/20 0.44
ABCB11 O95342 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3828111 0.85 SLC16A1 (0.70) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL5093483 0.84 SLC16A1 (0.69) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL5093486 0.83 SLC16A1 (0.68) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL5096845 0.83 SLC16A1 (0.67) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL3826454 0.81 SLC16A1 (1.00) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL23958362 0.81 SLC16A1 (1.00) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL3826451 0.81 SLC16A1 (1.00) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7
SCHEMBL19759433 0.80 SLC16A1 (0.63) SLC16A1CYP2C9CYP3A4SLC16A3ABCB11
SCHEMBL17942426 0.78 SLC16A1 (0.61) SLC16A1CYP2C9CYP3A4SLC16A3ABCB11
SCHEMBL26200805 0.78 SLC16A1 (0.85) SLC16A1CYP2C9CYP3A4SLC16A3SLC16A7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210338579-A1 pH RESPONSIVE BLOCK COPOLYMER COMPOSITIONS AND MICELLES THAT INHIBIT MCT 1 AND RELATED PROTEINS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210338579-A1 pH RESPONSIVE BLOCK COPOLYMER COMPOSITIONS AND MICELLES THAT INHIBIT MCT 1 AND RELATED PROTEINS MCTS1, ABCC1, PHLPP1 SLC16A1 4/4885CYP2C9 4842/4885CYP3A4 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.