Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184934 | 0.79 | DYRK1A (0.44) | DYRK1APDE4DHCAR2LMNAL3MBTL1 | |
| SCHEMBL15824828 | 0.79 | DYRK1A (0.44) | DYRK1APDE4DHCAR2LMNAL3MBTL1 | |
| SCHEMBL8597031 | 0.77 | DYRK1A (0.42) | DYRK1APDE4DHCAR2LMNAL3MBTL1 | |
| SCHEMBL7902863 | 0.74 | KDM4C (0.53) | DYRK1APDE4DLMNAL3MBTL1RAB9A | |
| SCHEMBL19451625 | 0.69 | DYRK1A (0.34) | DYRK1A | |
| SCHEMBL459546 | 0.68 | DYRK1A (0.42) | DYRK1A | |
| SCHEMBL14879418 | 0.67 | HCAR2 (0.48) | DYRK1APDE4DHCAR2LMNAL3MBTL1 | |
| SCHEMBL31386781 | 0.67 | HCAR2 (0.39) | DYRK1APDE4DHCAR2LMNAL3MBTL1 | |
| SCHEMBL30107036 | 0.64 | HCAR2 (0.42) | DYRK1APDE4DHCAR2LMNAL3MBTL1 | |
| SCHEMBL7806001 | 0.63 | PDE4D (0.38) | PDE4DHCAR2LMNAL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222442-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS | PLEXXIKON INC. (US) | 2021-11-04 | — | — | WO | disclosed |