Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115860 | 0.82 | KDM4C (0.67) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL169816 | 0.80 | KDM4C (0.50) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL27140315 | 0.80 | PDE4D (0.59) | ALDH1A1HSD17B10MAPK1PDE4DLMNA | |
| SCHEMBL9038005 | 0.80 | KDM4C (0.50) | KDM4CALDH1A1HSD17B10MAPK1NPSR1 | |
| SCHEMBL23294471 | 0.80 | KDM4C (0.50) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL4650087 | 0.80 | KDM4C (0.50) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL11204987 | 0.77 | KDM4C (0.47) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL11205400 | 0.77 | KDM4C (0.47) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL171417 | 0.76 | KDM4C (0.46) | KDM4CALDH1A1HSD17B10ARMAPK1 | |
| SCHEMBL20471480 | 0.76 | KDM4C (0.46) | KDM4CALDH1A1HSD17B10MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824393-A | Preparation method of 3, 4-dimethylpyrazole-5-formate compound | 中国科学院大连化学物理研究所 | 2021-05-21 | — | — | CN | disclosed |
| CN-106608873-A | Pyrazole amide compound, and preparation method and application thereof | 湖南化工研究院有限公司 | 2017-05-03 | — | — | CN | disclosed |
| US-6297386-B1 | BY REACTING THE ENOLATE OF A 2,4-DIKETOCARBOXYLIC ESTER IN THE PRESENCE OF A SOLVENT AND WATER WITH AN N-ALKYLHYDRAZINIUM SALT,PARTICULARLY ECONOMICAL PREPARATION OF AND WITH ONLY LIMITED FORMATION OF UNDESIRABLE ISOMERS. PATENT NUMBER: | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-02 | — | — | US | disclosed |
| US-5977378-A | Process for the preparation of 1-alkyl-pyrazole-5-carboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |