Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511079 | 0.82 | CYP1A1 (0.50) | CYP1A1CYP1A2CYP1B1GAANPC1 | |
| SCHEMBL29180421 | 0.81 | AKR1C3 (0.48) | CYP1A1CYP1A2CYP1B1GAAALDH1A1 | |
| SCHEMBL23980604 | 0.81 | CYP1A2 (0.59) | CYP1A1CYP1A2CYP1B1RAB9A | |
| SCHEMBL8637909 | 0.81 | AKR1C3 (0.52) | CYP1A1CYP1A2CYP1B1GAAALDH1A1 | |
| SCHEMBL29740644 | 0.81 | AKR1C3 (0.52) | CYP1A1CYP1A2CYP1B1GAAALDH1A1 | |
| SCHEMBL7502871 | 0.80 | CYP1A2 (0.59) | CYP1A1CYP1A2CYP1B1RAB9A | |
| SCHEMBL21551821 | 0.78 | AKR1C3 (0.45) | CYP1A2GAAALDH1A1MCL1AKR1C3 | |
| SCHEMBL29740639 | 0.78 | AKR1C3 (0.45) | CYP1A2GAAALDH1A1MCL1AKR1C3 | |
| SCHEMBL11496731 | 0.75 | ALDH1A1 (0.63) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL23980611 | 0.75 | NQO1 (0.46) | CYP1A1CYP1A2CYP1B1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222542-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-04 | — | — | WO | disclosed |