Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143242 | 0.85 | MAPT (0.38) | PTGER4PPARGPDE10AKDM4EALDH1A1 | |
| SCHEMBL31143304 | 0.85 | MAPT (0.38) | PTGER4PPARGPDE10AKDM4EALDH1A1 | |
| SCHEMBL30798199 | 0.81 | TP53 (0.44) | PTGER4ADORA2AKDM4EALDH1A1MAPT | |
| SCHEMBL25544377 | 0.79 | PPARG (0.45) | PTGER4PPARGKDM4EALDH1A1IAPP | |
| SCHEMBL31202954 | 0.78 | ACSS2 (0.46) | KDM4EALDH1A1MAPTLMNADRD2 | |
| SCHEMBL26237230 | 0.78 | ACSS2 (0.46) | KDM4EALDH1A1MAPTLMNADRD2 | |
| SCHEMBL20288189 | 0.76 | GLP1R (0.42) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL29480799 | 0.76 | GLP1R (0.42) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL20280071 | 0.76 | GLP1R (0.42) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL29480797 | 0.76 | GLP1R (0.42) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |