Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25544377 | 0.83 | PPARG (0.45) | TP53ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL23980785 | 0.81 | PTGER4 (0.36) | TP53TLR7GAAALDH1A1KDM4E | |
| SCHEMBL31143304 | 0.80 | MAPT (0.38) | TP53GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL31143242 | 0.80 | MAPT (0.38) | TP53GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL20280071 | 0.78 | GLP1R (0.42) | GLP1RGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL29480799 | 0.78 | GLP1R (0.42) | GLP1RGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL20288189 | 0.78 | GLP1R (0.42) | GLP1RGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL29480797 | 0.78 | GLP1R (0.42) | GLP1RGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL30259555 | 0.78 | GLP1R (0.41) | GLP1RGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL29924291 | 0.78 | PTGER4 (0.35) | MAPTPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |