Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659413 | 0.82 | MAPK1 (0.47) | GPR119MAPTKDM4ETHRBNAMPT | |
| SCHEMBL23980945 | 0.81 | GPR119 (0.45) | GPR119MAPTKDM4ETHRBNAMPT | |
| SCHEMBL21198677 | 0.80 | ADRB1 (0.52) | HTR1A | |
| SCHEMBL29691314 | 0.79 | GPR119 (0.57) | GPR119MAPTKDM4ETHRBNAMPT | |
| SCHEMBL23210070 | 0.79 | GPR119 (0.57) | GPR119MAPTKDM4ETHRBNAMPT | |
| SCHEMBL25403420 | 0.79 | MEN1 (0.43) | NAMPTUTS2R | |
| SCHEMBL27288015 | 0.79 | MEN1 (0.43) | NAMPTUTS2R | |
| SCHEMBL23980870 | 0.79 | MEN1 (0.43) | NAMPTUTS2R | |
| SCHEMBL3281416 | 0.79 | MAPK1 (0.46) | HTR1AGPR119NAMPT | |
| SCHEMBL25723375 | 0.79 | MAPT (0.50) | GPR119MAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |