Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29128812 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL27751503 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL27548223 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL28428049 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL28553503 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL28093042 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL28013567 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| Bromide SCHEMBL27476062 | 0.98 | TBXAS1 (0.47) | CYP17A1TBXAS1KDM4EKMT2A | |
| SCHEMBL2398555 | 0.98 | TBXAS1 (0.46) | CYP17A1TBXAS1KDM4EKMT2ACYP19A1 | |
| SCHEMBL11871891 | 0.98 | TBXAS1 (0.46) | CYP17A1TBXAS1KDM4EKMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113652015-A | Sun-proof natural latex foam material and preparation method thereof | 江苏金世缘乳胶制品股份有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-112321909-A | High-strength wear-resistant natural rubber composite material and preparation method thereof | 侯光宇 | 2021-02-05 | — | — | CN | claimed |
| CN-104130236-A | Normal-pressure CO2 catalytic conversion cyclic carbonate synthesis method | BEIJING INST TECHNOLOGY | 2014-11-05 | — | — | CN | claimed |
| CN-113652015-A | Sun-proof natural latex foam material and preparation method thereof | 江苏金世缘乳胶制品股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-112321909-A | High-strength wear-resistant natural rubber composite material and preparation method thereof | 侯光宇 | 2021-02-05 | — | — | CN | disclosed |
| CN-104130236-A | Normal-pressure CO2 catalytic conversion cyclic carbonate synthesis method | BEIJING INST TECHNOLOGY | 2014-11-05 | — | — | CN | disclosed |
| CN-103601665-A | Method of extracting amino acid by aqueous two phase system based on ionic liquid | DALIAN JIEXIN BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2014-02-26 | — | — | CN | disclosed |
| US-8597517-B2 | Process of recovery of exhausted ionic liquids used in the extractive desulfurization of naphthas | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2013-12-03 | — | — | US | disclosed |
| CN-102267933-B | Tryptophan extraction process with aqueous two-phase system based on amide functional ionic liquid | UNIV DALIAN | 2013-06-05 | — | — | CN | disclosed |
| CN-102267933-A | Tryptophan extraction process with aqueous two-phase system based on amide functional ionic liquid | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110215052-A1 | Process of recovery of exhausted ionic liquids used in the extractive desulfurization of naphthas | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2011-09-08 | — | — | US | disclosed |
| CN-101492422-B | Alkyl imidazole succinimide ionic liquid and method for preparing the same | UNIV EAST CHINA NORMAL | 2010-12-01 | — | — | CN | disclosed |
| CN-101492422-A | Alkyl imidazole succinimide ionic liquid and method for preparing the same | UNIV EAST CHINA NORMAL (CN) | 2009-07-29 | — | — | CN | disclosed |
| CN-101402590-A | Novel ion liquid based on cyano-acyl amine anion and method of preparing the same | UNIV EAST CHINA NORMAL (CN) | 2009-04-08 | — | — | CN | disclosed |
| CN-100471843-C | Ultra-high purity ionic liquids | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1854129-A | Ultra-high purity ionic liquids | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2006-11-01 | — | — | CN | disclosed |