Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27751503 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL28013567 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL28553503 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL27548223 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL28428049 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL27476062 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL29128812 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP17A1KDM4EKMT2A | |
| SCHEMBL10456414 | 0.98 | TBXAS1 (0.49) | TBXAS1CYP17A1KDM4EKMT2A | |
| SCHEMBL16163925 | 0.98 | TBXAS1 (0.49) | TBXAS1CYP17A1KDM4EKMT2A | |
| Bromide SCHEMBL2398121 | 0.98 | CYP17A1 (0.44) | TBXAS1CYP17A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029621-B | The technique that alkyl aromatic compound is oxidized to aromatic carboxylic acid | 信实工业公司 | 2019-03-26 | — | — | CN | claimed |
| CN-106029621-A | Process for oxidation of alkyl aromatic compound to aromatic carboxylic acid | 信实工业公司 | 2016-10-12 | — | — | CN | claimed |
| CN-106029621-B | The technique that alkyl aromatic compound is oxidized to aromatic carboxylic acid | 信实工业公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-106029621-A | Process for oxidation of alkyl aromatic compound to aromatic carboxylic acid | 信实工业公司 | 2016-10-12 | — | — | CN | disclosed |