Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26712522 | 1.00 | KDM4C (0.47) | KDM4CALDH1A1MAPTL3MBTL1ATM | |
| SCHEMBL18365987 | 0.82 | KDM4E (0.51) | ALDH1A1MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL177762 | 0.77 | ALDH1A1 (0.57) | KDM4CALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL28133307 | 0.77 | ALDH1A1 (0.57) | KDM4CALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL30142073 | 0.77 | ALDH1A1 (0.57) | KDM4CALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL2084609 | 0.76 | KMT2A (0.55) | ALDH1A1MAPTL3MBTL1ATMRAB9A | |
| SCHEMBL29755206 | 0.76 | KMT2A (0.55) | ALDH1A1MAPTL3MBTL1ATMRAB9A | |
| SCHEMBL2392771 | 0.76 | KMT2A (0.55) | ALDH1A1MAPTL3MBTL1ATMRAB9A | |
| Hydrochloric Acid SCHEMBL177902 | 0.76 | ALDH1A1 (0.56) | KDM4CALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL30557096 | 0.73 | KDM4E (0.47) | MAPTL3MBTL1RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222556-A1 | PI3K-α INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |