⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989843 | 0.81 | — | — | |
| SCHEMBL23990274 | 0.80 | — | — | |
| SCHEMBL23991150 | 0.79 | — | — | |
| SCHEMBL23989505 | 0.69 | ALOX5 (0.35) | — | |
| SCHEMBL20156237 | 0.69 | — | — | |
| SCHEMBL24103786 | 0.67 | — | — | |
| SCHEMBL23138191 | 0.67 | MEN1 (0.36) | — | |
| SCHEMBL15923864 | 0.67 | — | — | |
| SCHEMBL24103603 | 0.63 | — | — | |
| SCHEMBL23991003 | 0.62 | NPSR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220183-A1 | IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2021-11-04 | — | — | WO | disclosed |
| WO-2021222404-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN BIOTECH, INC. (US) | 2021-11-04 | — | — | WO | disclosed |