Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.61 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.61 |
| ▸ | TSPO | P30536 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CETP | P11597 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GMNN | O75496 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711520 | 1.00 | S1PR1 (0.61) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL28591577 | 0.82 | S1PR1 (0.65) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL28271876 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL2721772 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL526072 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL12922735 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL3822887 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL29281204 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL12966636 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL13009766 | 0.77 | SPHK2 (0.67) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854878-A4 | SYNTHESIS OF GLYCOCONJUGATES OF THE LEWIS Y EPITOPE AND USES THEREOF | SLOAN KETTERING INST CANCER (US) | 2004-03-24 | — | — | EP | claimed |
| WO-2003101937-A1 | SYNTHETIC METHODS FOR THE LARGE SCALE PRODUCTION FROM GLUCOSE OF ANALOGS OF SPHINGOSINE, AZIDOSPHINGOSINE, CERAMIDES, LACTOSYL CERAMIDES, AND GLYCOSYL PHYTOSPHINGOSINE | BUNDLE DAVID R (CA) | 2003-12-11 | — | — | WO | claimed |
| US-20020038017-A1 | Synthesis of glycoconjugates of the lewis y epitope and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2002-03-28 | — | — | US | claimed |
| EP-0854878-A1 | SYNTHESIS OF GLYCOCONJUGATES OF THE LEWIS Y EPITOPE AND USES THEREOF | Sloan-Kettering Institute For Cancer Research (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0724562-B1 | SYNTHESIS OF SPHINGOSINES | VIRGINIA TECH INTELL PROP (US) | 1998-06-03 | — | — | EP | claimed |
| WO-1997003995-A1 | SYNTHESIS OF GLYCOCONJUGATES OF THE LEWIS Y EPITOPE AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-02-06 | — | — | WO | claimed |
| EP-0724562-A1 | SYNTHESIS OF SPHINGOSINES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-08-07 | — | — | EP | claimed |
| US-5488167-A | Synthesis of sphingosines | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-01-30 | — | — | US | claimed |
| US-5449836-A | Acetal derivative chemical intermediates | RHONE-POULENC NUTRITION ANIMALE (FR) | 1995-09-12 | — | — | US | claimed |
| WO-1995011222-A1 | SYNTHESIS OF SPHINGOSINES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1995-04-27 | — | — | WO | claimed |
| US-4918170-A | Process for producing gangliosides | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | claimed |
| JP-8053488-A | — | — | None | — | — | JP | disclosed |
| JP-2049795-A | — | — | None | — | — | JP | disclosed |
| JP-3101691-A | — | — | None | — | — | JP | disclosed |
| US-9586984-B2 | One-pot synthesis of alpha/beta-O-glycolipids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-07 | — | — | US | disclosed |
| US-5380832-A | Ganglioside GM3 analogs | THE NISSHIN OIL MILLS, LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| JP-H03101691-A | GANGLIOSIDES AND INTERMEDIATE THEREFOR | WAKO PURE CHEM IND LTD | 1991-04-26 | — | — | JP | disclosed |
| US-4918170-A | Process for producing gangliosides | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4918170-A | Process for producing gangliosides | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| JP-H0249795-A | NOVEL PRODUCTION PROCESS FOR GANGLIOSIDES | WAKO PURE CHEM IND LTD | 1990-02-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038017-A1 | Synthesis of glycoconjugates of the lewis y epitope and uses thereof | UGCG, SGMS1, CERT1 | S1PR1 77/4885ALDH1A1 2996/4885S1PR4 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.