Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.61 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.61 |
| ▸ | TSPO | P30536 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CETP | P11597 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GMNN | O75496 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398671 | 1.00 | S1PR1 (0.61) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL28591577 | 0.82 | S1PR1 (0.65) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL28271876 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL2721772 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL526072 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL12922735 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL3822887 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL29281204 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL12966636 | 0.79 | SPHK2 (0.69) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 | |
| SCHEMBL13009766 | 0.77 | SPHK2 (0.67) | S1PR1ALDH1A1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724562-B1 | SYNTHESIS OF SPHINGOSINES | VIRGINIA TECH INTELL PROP (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0724562-A1 | SYNTHESIS OF SPHINGOSINES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5488166-A | Synthesis of sphingosines | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-01-30 | — | — | US | disclosed |
| US-5488167-A | Synthesis of sphingosines | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995011222-A1 | SYNTHESIS OF SPHINGOSINES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1995-04-27 | — | — | WO | disclosed |