Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835941 | 0.82 | ALDH1A1 (0.38) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| SCHEMBL27423951 | 0.76 | GRIK1 (0.40) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| SCHEMBL1582982 | 0.76 | GRIK1 (0.40) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| SCHEMBL909602 | 0.76 | ALDH1A1 (0.44) | CTSAALDH1A1NPC1RAB9A | |
| SCHEMBL11083464 | 0.76 | GRIK1 (0.40) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| SCHEMBL27787271 | 0.76 | ALDH1A1 (0.40) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| Hydrochloric Acid SCHEMBL11087078 | 0.74 | GRIK1 (0.40) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| SCHEMBL22313545 | 0.73 | — | — | |
| SCHEMBL28281362 | 0.73 | GAA (0.46) | CTSAALDH1A1NPC1RAB9AADAM17 | |
| SCHEMBL9179616 | 0.73 | CTSA (0.41) | CTSAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380884-B1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8497382-B2 | Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-07-30 | — | — | US | disclosed |
| EP-2380884-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110237630-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237630-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | PPARA, PPARD, PPARG | CTSA 1785/4885ALDH1A1 305/4885NPC1 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.