Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983388 | 0.88 | ALDH1A1 (0.48) | ALDH1A1CTSALMNATSHRFFAR2 | |
| SCHEMBL27657617 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CTSALMNATSHRFFAR2 | |
| SCHEMBL1007892 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CTSALMNATSHRFFAR2 | |
| SCHEMBL3561711 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CTSALMNATSHRFFAR2 | |
| Oxalic Acid SCHEMBL7013062 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CTSALMNATSHRNPC1 | |
| SCHEMBL908619 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CTSALMNATSHRNPC1 | |
| SCHEMBL2398682 | 0.76 | CTSA (0.40) | ALDH1A1CTSANPC1RAB9A | |
| SCHEMBL1582982 | 0.76 | GRIK1 (0.40) | ALDH1A1CTSALMNATSHRNPC1 | |
| SCHEMBL14433353 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CTSALMNATSHRFFAR2 | |
| SCHEMBL11083464 | 0.76 | GRIK1 (0.40) | ALDH1A1CTSALMNATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021688-B1 | 7-(THIAZOLYLPROPIONAMIDO) CEPHALOSPORINS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-07-13 | — | — | EP | claimed |
| CN-110740996-B | Covalent small molecule DCN1 inhibitors and methods of treatment using the same | 密执安大学评议会 | 2024-01-09 | — | — | CN | disclosed |
| EP-2978747-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978754-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| US-9150526-B2 | Biaryl-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-10-06 | — | — | US | disclosed |
| CN-102056917-B | Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists | MERCK & CO INC | 2014-11-05 | — | — | CN | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296296-A1 | Biaryl-Propionic Acid Derivatives and their Use as Pharmaceuticals | SANOFI (FR) | 2014-10-02 | — | — | US | disclosed |
| CN-102391255-B | Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME | 2014-07-09 | — | — | CN | disclosed |
| WO-2009124166-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009123870-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009123870-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| WO-2005115148-A1 | 3-ARYL-3-HYDROXY-2-METHYLENEPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
| US-4581353-A | ANTIBIOTIC, BACTERICIDE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0021688-B1 | 7-(THIAZOLYLPROPIONAMIDO) CEPHALOSPORINS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-07-13 | — | — | EP | disclosed |
| EP-0021688-A1 | 7-(Thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021688-A1 | 7-(Thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296296-A1 | Biaryl-Propionic Acid Derivatives and their Use as Pharmaceuticals | CTSV, F2R, CTSF | ALDH1A1 269/4885CTSA 22/4885LMNA 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.