Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.75 |
| ▸ | NPC1 | O15118 | 9/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348462 | 0.85 | POLB (0.70) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL31610757 | 0.84 | RAB9A (1.00) | RAB9ANPC1KMT2APOLBTP53 | |
| SCHEMBL6783579 | 0.84 | RAB9A (1.00) | RAB9ANPC1KMT2APOLBTP53 | |
| SCHEMBL30051982 | 0.83 | MEN1 (0.77) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL9637653 | 0.83 | MEN1 (0.77) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL7849600 | 0.83 | RAB9A (0.71) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL5853939 | 0.83 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL30354462 | 0.83 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL9190814 | 0.83 | KMT2A (1.00) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL4117858 | 0.82 | RAB9A (0.67) | RAB9ANPC1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338610-A1 | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | HEPANOVA, INC. | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338610-A1 | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | AADAC, GOT2, ABAT | RAB9A 2856/4885NPC1 166/4885MEN1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.