Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | PRKDC | P78527 | 3/20 | 0.49 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23150559 | 0.89 | MTOR (0.63) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL23251625 | 0.88 | MTOR (0.62) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL24519483 | 0.87 | MTOR (0.61) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL23988089 | 0.86 | MTOR (0.60) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL25113256 | 0.84 | MTOR (0.58) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL29867929 | 0.84 | MTOR (0.58) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL30740011 | 0.84 | MTOR (0.58) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL23251924 | 0.84 | MTOR (0.58) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL20553360 | 0.84 | MTOR (0.58) | MTORHDAC1PIK3CDPIK3CGPIK3CA | |
| SCHEMBL24519509 | 0.84 | MTOR (0.59) | MTORHDAC1PIK3CDPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338824-A1 | C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338824-A1 | C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors | MTOR, RICTOR, RPTOR | MTOR 1/4885HDAC1 526/4885PIK3CD 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.