Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | RHEB | Q15382 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL280428 | 0.80 | ALDH1A1 (0.55) | AHRPARP1RHEBTRPA1CA1 | |
| SCHEMBL29628855 | 0.80 | ALDH1A1 (0.55) | AHRPARP1RHEBTRPA1CA1 | |
| Water SCHEMBL3636507 | 0.78 | ALDH1A1 (0.52) | AHRPARP1RHEBTRPA1CA1 | |
| Bromide SCHEMBL7761036 | 0.78 | ALDH1A1 (0.52) | AHRPARP1RHEBTRPA1CA1 | |
| Iodide SCHEMBL6832071 | 0.78 | ALDH1A1 (0.52) | AHRPARP1RHEBTRPA1CA1 | |
| Hydrochloric Acid SCHEMBL7799642 | 0.78 | ALDH1A1 (0.52) | AHRPARP1RHEBTRPA1CA1 | |
| SCHEMBL4420829 | 0.76 | AOC3 (0.38) | AHRPARP1RHEBNR4A2CYP2A6 | |
| SCHEMBL4418490 | 0.76 | AHR (0.36) | AHRPARP1RHEBPIK3CDGAA | |
| SCHEMBL2126075 | 0.76 | HPRT1 (0.58) | AHRPARP1RHEBTRPA1CA1 | |
| Water SCHEMBL10356864 | 0.76 | ALDH1A1 (0.50) | AHRPARP1RHEBTRPA1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | claimed |
| EP-1720615-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-11-15 | — | — | EP | claimed |
| WO-2005087187-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-22 | — | — | WO | claimed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | claimed |
| EP-1409480-A1 | PYRROLO-INDOLE AND PYRROLO-QUINOLINE DERIVATIVES AS PRODRUGS FOR TUMOUR TREATMENT | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2004-04-21 | — | — | EP | claimed |
| WO-2002068412-A1 | PYRROLO-INDOLE AND PYRROLO-QUINOLINE DERIVATIVES AS PRODRUGS FOR TUMOUR TREATMENT | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-09-06 | — | — | WO | claimed |
| EP-0680964-B1 | PYRROLO [3,2-e]INDOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE | UNIV SANTIAGO COMPOSTELA (ES) | 2002-01-16 | — | — | EP | claimed |
| EP-0680964-A1 | NEW PIRROLO 3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-11-08 | — | — | EP | claimed |
| WO-1995014022-A1 | NEW PIRROLO [3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-05-26 | — | — | WO | claimed |
| CN-118852180-A | Alkylated benzo 3, 6-dihydropyrrole [3,2-E ] indole molecule and preparation method, application, hydrogen storage method and hydrogen release method thereof | 北京化工大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| US-8017640-B2 | Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment | UNIVERSITY OF BRADFORD (GB) | 2011-09-13 | — | — | US | disclosed |
| EP-0680964-B1 | PYRROLO [3,2-e]INDOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE | UNIV SANTIAGO COMPOSTELA (ES) | 2002-01-16 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |
| EP-0680964-A1 | NEW PIRROLO 3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-11-08 | — | — | EP | disclosed |
| WO-1995014022-A1 | NEW PIRROLO [3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-05-26 | — | — | WO | disclosed |
| US-4916217-A | Phosphorus containing derivatives of epipodophyllotoxin | BRISTOL-MYERS COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | AHR 988/4885PARP1 1932/4885RHEB 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.