Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | ATP4A | P20648 | 4/20 | 0.39 |
| ▸ | ATP4B | P51164 | 4/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 2/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.38 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.38 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586438 | 0.85 | AGXT (0.55) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL29662197 | 0.85 | AGXT (0.55) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL28797303 | 0.83 | AGXT (0.53) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL23988600 | 0.80 | SARM1 (0.44) | AGXTATP4AATP4BSARM1ATP1A1 | |
| SCHEMBL22699665 | 0.79 | AGXT (0.52) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL29382857 | 0.77 | AGXT (0.66) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL1060082 | 0.77 | AGXT (0.66) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL154027 | 0.77 | AGXT (0.66) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL8830165 | 0.76 | AGXT (0.46) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 | |
| SCHEMBL3022770 | 0.76 | AGXT (0.46) | AGXTPDE10AHSP90AA1KMT2AHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | AGXT 900/4885PDE10A 348/4885HSP90AA1 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.