Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403143 | 1.00 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2GLS | |
| SCHEMBL2617177 | 0.83 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL2309189 | 0.83 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL21689917 | 0.83 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL24324458 | 0.82 | CYP17A1 (0.57) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL10890972 | 0.82 | ITGB3 (0.61) | PPARGPPARACYP17A1ITGB3ITGA2B | |
| SCHEMBL18181212 | 0.81 | CYP17A1 (0.56) | PPARGPPARACYP17A1PTGDR2GLS | |
| SCHEMBL977842 | 0.81 | PTGDR2 (0.60) | PPARGPPARACYP17A1PTGDR2GLS | |
| SCHEMBL27916490 | 0.80 | CYP17A1 (0.54) | PPARGPPARACYP17A1PTGDR2ITGB3 | |
| SCHEMBL408439 | 0.79 | CYP17A1 (0.59) | PPARGPPARACYP17A1PTGDR2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-17 | — | — | US | disclosed |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | PPARG 1761/4885PPARA 3027/4885CYP17A1 3546/4885 |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | PPARG 1761/4885PPARA 3027/4885CYP17A1 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.