Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005881 | 0.98 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Hydrochloric Acid SCHEMBL27760619 | 0.86 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27827627 | 0.84 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Hydrochloric Acid SCHEMBL28198021 | 0.83 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28262372 | 0.83 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4 | |
| Bromide SCHEMBL27827626 | 0.83 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Hydrochloric Acid SCHEMBL15155490 | 0.82 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27336395 | 0.80 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Iodide SCHEMBL27806989 | 0.80 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL28164249 | 0.80 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332660-A1 | Stable Aqueous Compositions of Fertilizer and Agriculturally Active Compound | BASF SE (DE) | 2022-10-20 | — | — | US | disclosed |
| US-20220287301-A1 | POLYMERS FOR SPRAY DRIFT CONTROL OF PESTICIDE SPRAY | BASF SE (DE) | 2022-09-15 | — | — | US | disclosed |
| EP-4038038-A1 | STABLE AQUEOUS COMPOSITIONS OF FERTILIZER AND AGRICULTURALLY ACTIVE COMPOUND | BASF SE (DE) | 2022-08-10 | — | — | EP | disclosed |
| EP-4025053-A1 | POLYMERS FOR SPRAY DRIFT CONTROL OF PESTICIDE SPRAY | BASF SE (DE) | 2022-07-13 | — | — | EP | disclosed |
| CN-114340391-A | Polymers for spray drift control of pesticide sprays | 巴斯夫欧洲公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021063885-A1 | STABLE AQUEOUS COMPOSITIONS OF FERTILIZER AND AGRICULTURALLY ACTIVE COMPOUND | BASF SE (DE) | 2021-04-08 | — | — | WO | disclosed |
| CN-104870546-B | Rubber composition and formed body | 日本瑞翁株式会社 | 2017-06-13 | — | — | CN | disclosed |
| US-8754155-B2 | Delivery system for releasing silicone ingredients | DOW CORNING CORPORATION (US) | 2014-06-17 | — | — | US | disclosed |
| CN-101258232-B | Delivery system for releasing silicone ingredients | DOW CORNING | 2013-02-06 | — | — | CN | disclosed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20070197736-A1 | Molded Woody Article And Process For Producing Molded Woody Article | NOF CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| WO-2007028773-A1 | DELIVERY SYSTEM FOR RELEASING SILICONE INGREDIENTS | DOW CORNING CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |
| EP-1731279-A1 | MOLDED WOODY ARTICLE AND PROCESS FOR PRODUCING MOLDED WOODY ARTICLE | Toyota Boshoku Kabushiki Kaisya (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-1307175-B8 | HAIR STYLING COMPOSITION | UNILEVER PLC (GB) | 2006-06-14 | — | — | EP | disclosed |
| EP-1450755-A1 | HAIR STYLING COMPOSITION | UNILEVER PLC (GB) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003047538-A1 | HAIR STYLING COMPOSITION | UNILEVER PLC (GB) | 2003-06-12 | — | — | WO | disclosed |
| EP-1307175-A2 | HAIR STYLING COMPOSITION | Unilever Plc (GB) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002011686-A2 | HAIR STYLING COMPOSITION | UNILEVER PLC (GB) | 2002-02-14 | — | — | WO | disclosed |
| EP-1161459-A1 | INTERPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000047631-A1 | INTERPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220287301-A1 | POLYMERS FOR SPRAY DRIFT CONTROL OF PESTICIDE SPRAY | DDT, PARG, PLD2 | TSHR 3183/4885HPGD 4358/4885ALDH1A1 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.