Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AHCY | P23526 | 3/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989265 | 1.00 | ADORA3 (0.51) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL3235909 | 1.00 | ADORA3 (0.51) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL3236868 | 1.00 | ADORA3 (0.51) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL13429417 | 1.00 | ADORA3 (0.51) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL14511243 | 1.00 | ADORA3 (0.51) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL18574251 | 0.87 | ADORA3 (0.49) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL23906524 | 0.87 | ADORA3 (0.49) | ADORA3AHCYDOT1LPI4KAPI4K2B | |
| SCHEMBL5696096 | 0.87 | AHCY (0.51) | AHCYDOT1LPDE4APDE4BPDE4C | |
| SCHEMBL5696093 | 0.86 | AHCY (0.46) | ADORA3AHCYDOT1LPDE4APDE4B | |
| SCHEMBL18520512 | 0.85 | PI4KA (0.51) | ADORA3AHCYDOT1LPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340169-A1 | CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF | SHANGHAI JEYOU PHARMACEUTICAL CO., LTD. (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340169-A1 | CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF | STING1, CGAS, TLR9 | ADORA3 353/4885AHCY 2106/4885DOT1L 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.