SCHEMBL2399012

SCHEMBL2399012

Cc1ccccc1C(F)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.46
ESR1 P03372 1/20 0.43
ALDH1A1 P00352 1/20 0.40
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
CTSA P10619 4/20 0.38
PTGS2 P35354 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
SLC6A9 P48067 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7030707 0.94 ACP3 (0.42) ACP3ESR1ALDH1A1SLC1A3SLC1A2
Ethylene Glycol SCHEMBL27792563 0.93 ACP3 (0.41) ACP3ESR1ALDH1A1CTSAKDM4E
SCHEMBL11091959 0.79 GABRA1 (0.45) PTGS2L3MBTL1
SCHEMBL4370114 0.78 ACP3 (0.48) ACP3ESR1ALDH1A1CTSAPOLB
SCHEMBL28459728 0.78 CYP2D6 (0.50) ACP3ESR1ALDH1A1POLBL3MBTL1
SCHEMBL2206363 0.78 SRC (0.50) ACP3ESR1ALDH1A1CTSAPOLB
SCHEMBL30136352 0.78 SRC (0.50) ACP3ESR1ALDH1A1CTSAPOLB
SCHEMBL168464 0.77 LMNA (0.52) ACP3ESR1ALDH1A1POLBL3MBTL1
SCHEMBL168463 0.77 LMNA (0.52) ACP3ESR1ALDH1A1POLBL3MBTL1
SCHEMBL19458984 0.77 CNR2 (0.50) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417509-A A kind of preparation method of phenylacetic acid compound 上海康鹏科技有限公司 2017-12-01 CN claimed
CN-107417509-A A kind of preparation method of phenylacetic acid compound 上海康鹏科技有限公司 2017-12-01 CN disclosed
CN-106660991-A Antiproliferative compounds and methods of use thereof 细胞基因公司 2017-05-10 CN disclosed
US-8252559-B2 Methods and systems for selective fluorination of organic molecules THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-08-28 US disclosed
US-8026085-B2 Methods and systems for selective fluorination of organic molecules CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2011-09-27 US disclosed
US-20090209010-A1 METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2009-08-20 US disclosed
EP-2069513-A2 METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES California Institute of Technology (US) 2009-06-17 EP disclosed
US-20090061471-A1 Methods and systems for selective fluorination of organic molecules INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2009-03-05 US disclosed
WO-2008016709-A9 METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES CALIFORNIA INST OF TECHN (US) 2008-05-29 WO disclosed
WO-2008016709-A2 METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2008-02-07 WO disclosed