Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 2/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896627 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL14777168 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL896976 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL11092309 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL568115 | 0.83 | ADRA2A (0.60) | SMN1; SMN2HTTHTR1AADRA2ADRD1 | |
| SCHEMBL407539 | 0.83 | ADRA2A (0.60) | SMN1; SMN2HTTHTR1AADRA2ADRD1 | |
| SCHEMBL30640286 | 0.83 | ADRA2A (0.60) | SMN1; SMN2HTTHTR1AADRA2ADRD1 | |
| SCHEMBL3266284 | 0.83 | ADRA2A (0.60) | SMN1; SMN2HTTHTR1AADRA2ADRD1 | |
| SCHEMBL14156093 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL8746467 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNACRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110236815-A1 | COATED CARRIERS | XEROX CORPORATION (US) | 2011-09-29 | — | — | US | claimed |
| US-20110236815-A1 | COATED CARRIERS | XEROX CORPORATION (US) | 2011-09-29 | — | — | US | disclosed |