Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640286 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL3266284 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL568115 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL9316602 | 0.88 | CA2 (0.58) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL28929697 | 0.86 | CA2 (0.53) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL1545537 | 0.85 | HTT (0.66) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL2399301 | 0.83 | SMN1; SMN2 (0.55) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL896627 | 0.83 | SMN1; SMN2 (0.55) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| Methyl Alcohol SCHEMBL10973093 | 0.81 | POLB (0.58) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL20445516 | 0.80 | ADRA2A (0.56) | ADRA2AADRA1AHTTHTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824646-B | Method for synthesizing optically pure 2-hydroxymethyl-1, 4-benzodioxan and derivative thereof | 陕西师范大学 | 2021-12-07 | — | — | CN | claimed |
| CN-109824646-A | A kind of method of the pure 2- methylol -1,4- benzodioxane of synthesizing optical and its derivative | 陕西师范大学 | 2019-05-31 | — | — | CN | claimed |
| CN-108250177-B | A kind of preparation method of 1,4- benzdioxan -2- formic acid | 上海馨远医药科技有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-108250177-A | A kind of preparation method of 1,4- benzodioxans -2- formic acid | 上海馨远医药科技有限公司 | 2018-07-06 | — | — | CN | claimed |
| CN-105061392-B | A kind of guanoxan sulfate synthetic method | 上海现代哈森（商丘）药业有限公司 | 2017-07-18 | — | — | CN | claimed |
| US-9616459-B1 | Polymeric coatings for fortification of visible, infrared, and laser optical devices | LOCKHEED MARTIN CORPORATION (US) | 2017-04-11 | — | — | US | claimed |
| WO-2008016199-A1 | PROCESS FOR THE PREPARATION OF CHIRAL 2-HYDROXYMETHYL-1,4-BENZODIOXANE COMPOUND | AHN-GOOK PHARMACEUTICAL CO., LTD. (KR) | 2008-02-07 | — | — | WO | claimed |
| US-20060004123-A1 | PHASE CHANGE INK PRINTING PROCESS | XEROX CORPORATION | 2006-01-05 | — | — | US | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| EP-1063235-B1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LTD (JP) | 2004-05-12 | — | — | EP | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| US-20030186976-A1 | Benzofurylpyrone derivatives | TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2003-10-02 | — | — | US | claimed |
| EP-0932609-B1 | AZAHETEROCYCLYMETHYL DERIVATIVES OF 2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO 2,3-e]INDOL-8-ONE | WYETH CORP (US) | 2003-05-14 | — | — | EP | claimed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | claimed |
| US-4539413-A | Preparation of 3-amino-1-[(1,4-benzodioxan)-2-yl-methoxy]-2-propanols | PIERRE FABRE S.A. (FR) | 1985-09-03 | — | — | US | claimed |
| EP-0037778-B1 | 2-(1,4-BENZODIOXANYL)-METHOXY-PROPANOL AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | PIERRE FABRE S.A. (FR) | 1983-12-28 | — | — | EP | claimed |
| JP-9297325-A | — | — | None | — | — | JP | disclosed |
| US-3957822-A | POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186976-A1 | Benzofurylpyrone derivatives | PLIN5, ACSL5, PLIN1 | ADRA2A 3121/4885ADRA1A 1793/4885HTT 2667/4885 |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ADRA2A 3319/4885ADRA1A 3475/4885HTT 2287/4885 |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ADRA2A 3163/4885ADRA1A 3418/4885HTT 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.