Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 18/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 18/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23994569 | 0.86 | KCNJ6 (0.34) | GRIN1GRIN2B | |
| SCHEMBL23994577 | 0.82 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL23995489 | 0.82 | GRIN1 (0.33) | GRIN1GRIN2B | |
| SCHEMBL23995464 | 0.82 | GRIN1 (0.33) | GRIN1GRIN2B | |
| SCHEMBL23995200 | 0.81 | HTR2C (0.34) | CHRNB2CHRNA4SLC6A4 | |
| SCHEMBL23994560 | 0.80 | PTGER3 (0.32) | CHRNB2CHRNA4 | |
| SCHEMBL23992997 | 0.79 | CHRNB2 (0.35) | CHRNB2CHRNA4GRIN1GRIN2B | |
| SCHEMBL23992773 | 0.78 | SLC6A4 (0.34) | CHRNB2CHRNA4SLC6A4 | |
| SCHEMBL23993425 | 0.77 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL30181579 | 0.77 | GRIN1 (0.31) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |