Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.34 |
| ▸ | HTR2A | P28223 | 6/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 6/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992773 | 0.90 | SLC6A4 (0.34) | HTR2CHTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23995261 | 0.86 | KCNJ6 (0.36) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL25006021 | 0.84 | HTR2A (0.38) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL23994880 | 0.83 | HTR2A (0.45) | HTR2CHTR2ASLC6A4HTR2BHTR1A | |
| SCHEMBL23994564 | 0.82 | HTR2A (0.39) | HTR2CHTR2AMAPK1HTR2BHTR1A | |
| SCHEMBL23994874 | 0.81 | SLC6A4 (0.36) | HTR2CHTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25589567 | 0.81 | HTR2A (0.32) | HTR2CHTR2AHTR2BKMO | |
| SCHEMBL23994573 | 0.81 | NT5E (0.36) | MAPK1CHRNB2CHRNA4 | |
| SCHEMBL23993255 | 0.81 | CHRNB2 (0.36) | SLC6A4CHRNB2CHRNA4 | |
| SCHEMBL25004763 | 0.80 | PDE1C (0.43) | HTR2CHTR2ASLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |