Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | AR | P10275 | 9/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993565 | 0.84 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23993608 | 0.82 | SLC6A4 (0.47) | SLC6A4ARTRPV4SLC6A2SLC6A3 | |
| SCHEMBL23995541 | 0.77 | AR (0.43) | SLC6A4ARTRPV4 | |
| SCHEMBL23995530 | 0.76 | HTR2A (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23993664 | 0.75 | AR (0.44) | SLC6A4ARSLC6A2SLC6A3 | |
| SCHEMBL23993667 | 0.75 | SLC6A4 (0.41) | SLC6A4ARSLC6A2SLC6A3 | |
| SCHEMBL23993627 | 0.73 | HTR2A (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23995533 | 0.72 | HTR2C (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23993579 | 0.71 | HTR2C (0.63) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18019012 | 0.71 | HTR2C (0.63) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |