Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.49 |
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | HTR2B | P41595 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993601 | 0.84 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL23993608 | 0.84 | SLC6A4 (0.47) | SLC6A4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL25005998 | 0.80 | TSHR (0.41) | SLC6A4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL23993664 | 0.78 | AR (0.44) | SLC6A4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL23993667 | 0.78 | SLC6A4 (0.41) | SLC6A4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL23995533 | 0.74 | HTR2C (0.50) | SLC6A4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL23993560 | 0.74 | HTR2A (0.41) | SLC6A4HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL2474594 | 0.72 | FFAR1 (0.52) | USP30 | |
| SCHEMBL4509439 | 0.72 | FFAR1 (0.52) | USP30 | |
| SCHEMBL15112858 | 0.72 | USP30 (0.47) | HTR2CUSP30TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |