Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24211769 | 0.89 | PTGS1 (0.55) | PTGS1POLBATMCA12CA1 | |
| SCHEMBL24212182 | 0.82 | CA12 (0.53) | PTGS1POLBATMCA12CA1 | |
| SCHEMBL14985425 | 0.78 | PTGS1 (0.59) | PTGS1ATMCA12CA1CA2 | |
| SCHEMBL24212178 | 0.77 | KMT2A (0.61) | POLBATMCA12CA1CA2 | |
| SCHEMBL8348726 | 0.76 | ADRB2 (0.71) | PTGS1POLBATMCA12CA1 | |
| SCHEMBL357406 | 0.76 | PTGS1 (0.64) | PTGS1POLBCA12CA1CA2 | |
| SCHEMBL2357109 | 0.76 | PTGS1 (0.64) | PTGS1ATMCA12CA1CA2 | |
| SCHEMBL3938664 | 0.75 | TRPV1 (0.63) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL18280764 | 0.75 | ALOX5 (0.67) | PTGS1KMT2ATRPV1MEN1 | |
| SCHEMBL29670774 | 0.75 | ALOX5 (0.67) | PTGS1KMT2ATRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | PCNA, POLM, MUS81 | PTGS1 2942/4885POLB 80/4885ATM 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.